Alectinib Hydrochloride [1256589-74-8]
HY-13011A
CAS Number1256589-74-8
Product group Chemicals
Estimated Purity98.06%
Molecular Weight519.08
Overview
- SupplierMedChem Express
- Product NameAlectinib Hydrochloride [1256589-74-8]
- Delivery Days Customer10
- CAS Number1256589-74-8
- Estimated Purity98.06%
- Molecular FormulaC30H35ClN4O2
- Molecular Weight519.08
- Scientific DescriptionAlectinib Hydrochloride (CH5424802 Hydrochloride; RO5424802 Hydrochloride; AF-802 Hydrochloride) is a potent, selective, and orally available ALK inhibitor with an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively. Alectinib demonstrates effective central nervous system (CNS) penetration.
- SMILES[H]Cl.N#CC1=CC2=C(C3=C(N2)C(C)(C4=CC(N5CCC(CC5)N6CCOCC6)=C(C=C4C3=O)CC)C)C=C1
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200