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Alectinib Hydrochloride [1256589-74-8]

HY-13011A
MedChem Express
CAS Number1256589-74-8
Product group Chemicals
Estimated Purity98.06%
Molecular Weight519.08
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Alectinib Hydrochloride [1256589-74-8]
  • Delivery Days Customer
    10
  • CAS Number
    1256589-74-8
  • Estimated Purity
    98.06%
  • Molecular Formula
    C30H35ClN4O2
  • Molecular Weight
    519.08
  • Scientific Description
    Alectinib Hydrochloride (CH5424802 Hydrochloride; RO5424802 Hydrochloride; AF-802 Hydrochloride) is a potent, selective, and orally available ALK inhibitor with an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively. Alectinib demonstrates effective central nervous system (CNS) penetration.
  • SMILES
    [H]Cl.N#CC1=CC2=C(C3=C(N2)C(C)(C4=CC(N5CCC(CC5)N6CCOCC6)=C(C=C4C3=O)CC)C)C=C1
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200