Almorexant hydrochloride [913358-93-7]
HY-10805A
CAS Number913358-93-7
Product group Chemicals
Estimated Purity99.28%
Molecular Weight549.02
Overview
- SupplierMedChem Express
- Product NameAlmorexant hydrochloride [913358-93-7]
- Delivery Days Customer10
- CAS Number913358-93-7
- CertificationResearch Use Only
- Estimated Purity99.28%
- Molecular FormulaC29H32ClF3N2O3
- Molecular Weight549.02
- Scientific DescriptionAlmorexant (ACT 078573) hydrochloride is an orally active, potent and competitive dual orexin receptor antagonist, with Kd values of 1.3 nM (OX1) and 0.17 nM (OX2), respectively. Almorexant hydrochloride reversibly blocks signaling of orexin-A and orexin-B peptides. Almorexant hydrochloride totally blocked the intracellular Ca2+ signal pathway. Almorexant hydrochloride stimulates caspase-3 activity in AsPC-1 cells and induces apoptosis.
- SMILESCNC([C@@H](C1=CC=CC=C1)N2CCC3=CC(OC)=C(OC)C=C3[C@@H]2CCC4=CC=C(C(F)(F)F)C=C4)=O.Cl
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200