alpha-Galactosylceramide Analog 8 [922727-14-8]

Name: alpha-Galactosylceramide Analog 8 [922727-14-8]
SKU: AG-CR1-3622_A27
Price: 267 EUR
Availability: InStock

AG-CR1-3622

Estimated Purity>96% (NMR)

Product group Chemicals

Molecular Weight868.3

Overview

Supplier
AdipoGen Life Sciences
Product Name
alpha-Galactosylceramide Analog 8 [922727-14-8]
Delivery Days Customer
10
Certification
Research Use Only
Estimated Purity
>96% (NMR)
Hazard Information
Non-hazardous
Molecular Formula
C50H97N3O8
Molecular Weight
868.3
Scientific Description
Chemical. CAS: 922727-14-8. Formula: C50H97N3O8. MW: 868.3. Synthetic. Immunostimulant. Potent stimulator of natural killer T (NKT) cells. Specific ligand of the lipid-binding MHC class I-like protein CD1d in human and mouse NKT cells. Potent antitumor compound. Stimulates the production of smaller amounts of IFN-gamma than alpha-GalCer, but induces equal or greater IL-4 secretion in mouse models. - Immunostimulant. Potent stimulator of natural killer T (NKT) cells. Specific ligand of the lipid-binding MHC class I-like protein CD1d in human and mouse NKT cells. Potent antitumor compound. Stimulates the production of smaller amounts of IFN-gamma than alpha-GalCer, but induces equal or greater IL-4 secretion in mouse models.
SMILES
CCCCCCCCCCCCCCCCCCCCCCCCC1=CN(N=N1)[C@@H](COC1OC(CO)C(O)C(O)C1O)[C@H](O)[C@H](O)CCCCCCCCCCCCCC
Storage Instruction
2°C to 8°C,-20°C
UNSPSC
12352200

Synthesis and evaluation of 1,2,3-triazole containing analogues of the immunostimulant alpha-GalCer: T. Lee, et al.; J. Med. Chem. 50, 585 (2007)
Phase transfer agent assisted biphasic CuAAC reaction: J.H. Kim & S. Kim; RSC Adv. 4, 26516 (2014)