alpha-Mannosylceramide [320610-63-7]

Name: alpha-Mannosylceramide [320610-63-7]
SKU: AG-CR1-3594_A27
Price: 288 EUR
Availability: InStock

AG-CR1-3594

Estimated Purity>95% (TLC)

Product group Chemicals

Molecular Weight858.3

Overview

Supplier
AdipoGen Life Sciences
Product Name
alpha-Mannosylceramide [320610-63-7]
Delivery Days Customer
10
Certification
Research Use Only
Estimated Purity
>95% (TLC)
Hazard Information
Non-hazardous
Molecular Formula
C50H99NO9
Molecular Weight
858.3
Scientific Description
Chemical. CAS: 320610-63-7. Formula: C50H99NO9. MW: 858.3. Potent stimulator of natural killer T (NKT) cells expressing the invariant Valpha19-Jalpha26 T cell receptor alpha chain (Valpha19 NKT cells). - Potent stimulator of natural killer T (NKT) cells expressing the invariant Valpha19-Jalpha26 T cell receptor alpha chain (Valpha19 NKT cells).
SMILES
CCCCCCCCCCCCCCCCCCCCCCCCCC(=O)N[C@@H](COC1OC(CO)C(O)C(O)C1O)[C@H](O)[C@H](O)CCCCCCCCCCCCCC
Storage Instruction
2°C to 8°C,-20°C
UNSPSC
12352200

CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides: T. Kawano, et al.; Science 278, 1626 (1997)
Synthetic alpha-mannosyl ceramide as a potent stimulant for an NKT cell repertoire bearing the invariant Valpha19-Jalpha26 TCR alpha chain: N. Okamoto, et al.; Chem. Biol. 12, 677 (2005)
MR1-restricted Valpha19i T cells: a second population recognizing lipid antigens?: J. Schumann & G. De Libero; Eur. J. Immunol. 37, 1724 (2007)
Induction of promotive rather than suppressive immune responses from a novel NKT cell repertoire Valpha19 NKT cell with alpha-mannosyl ceramide analogues consisting of the immunosuppressant ISP-I as the sphingosine unit: M. Shimamura, et al.; Eur. J. Med. Chem. 41, 569 (2006)
Modulation of Valpha19 NKT cell immune responses by alpha-mannosyl ceramide derivatives consisting of a series of modified sphingosines: M. Shimamura, et al.; Eur. J. Immunol. 37, 1836 (2007)
Glycolipid stimulators for NKT cells bearing invariant V alpha 19-J alpha 33 TCR alpha chains: M. Shimamura; MiniRev. Med. Chem. 8, 285 (2008)
Non-reducing end alpha-mannosylated glycolipids as potent activators for invariant Valpha19 TCR-bearing natural killer T cells: M. Shimamura; Carbohydr. Res. 343, 2010 (2008)