Alvelestat [848141-11-7]

MedChem Express

Alvelestat [848141-11-7]

10

848141-11-7

Research Use Only

95.43%

C25H22F3N5O4S

545.53

Alvelestat (AZD9668) is an orally bioavailable, affinity and selective inhibitor of neutrophil elastase (NE) with a pIC50 value of 7.9 nM, a Ki value of 9.4 nM and a Kd value of 9.5 nM.

O=C(C1=CC(C2=CC=NN2C)=C(C)N(C3=CC=CC(C(F)(F)F)=C3)C1=O)NCC4=NC=C(S(=O)(C)=O)C=C4

2°C to 8°C,-20°C,-80°C

12352200