AMG 837 calcium hydrate [1259389-38-2]

MedChem Express

AMG 837 calcium hydrate [1259389-38-2]

10

1259389-38-2

Research Use Only

98.45%

C26H21F3O3.1/2Ca.H2O

455.45

AMG 837 calcium hydrate is a potent, orally bioavailable and partial agonist of GPR40/FFA1. AMG 837 calcium hydrate inhibits specific [3H]AMG 837 binding at the human FFA1 receptor with a pIC50 of 8.13. AMG 837 calcium hydrate could enhance insulin secretion and lower glucose levels in rodents.

[O-]C(C[C@H](C#CC)C1=CC=C(C=C1)OCC2=CC=CC(C3=CC=C(C(F)(F)F)C=C3)=C2)=O.[0.5Ca2+].O

2°C to 8°C,-20°C,-80°C

12352200