AMI-1 [20324-87-2]

MedChem Express

AMI-1 [20324-87-2]

10

20324-87-2

Research Use Only

98%

C21H14N2Na2O9S2

548.45

AMI-1 is a potent, cell-permeable and reversible inhibitor of protein arginine N-methyltransferases (PRMTs), with IC50s of 8.8 microM and 3.0 microM for human PRMT1 and yeast-Hmt1p, respectively. AMI-1 exerts PRMTs inhibitory effects by blocking peptide-substrate binding.

O=C(NC1=CC2=CC(S(=O)(O[Na])=O)=CC(O)=C2C=C1)NC3=CC4=CC(S(=O)(O[Na])=O)=CC(O)=C4C=C3

2°C to 8°C,-20°C,-80°C

12352200