APD668 [832714-46-2]

MedChem Express

APD668 [832714-46-2]

10

832714-46-2

Research Use Only

95%

C21H24FN5O5S

477.51

APD668 is a potent, selective and orally active agonist of G-protein coupled receptor GPR119, with EC50s of 2.7 nM and 33 nM for hGPR119 and rGPR119, respectively. APD668 shows no significant inhibition of any of the five major CYP isoforms with the exception of CYP2C9 (Ki=0.1 microM). APD668 can be used for the research of steatohepatitis and diabetes.

O=C(OC(C)C)N(CC1)CCC1OC2=C3C(N(C4=CC=C(S(=O)(C)=O)C=C4F)N=C3)=NC=N2

2°C to 8°C,-20°C,-80°C

12352200