APS-2-79 [2002381-25-9]
HY-100627
CAS Number2002381-25-9
Product group Chemicals
Estimated Purity99.48%
Molecular Weight387.43
Overview
- SupplierMedChem Express
- Product NameAPS-2-79 [2002381-25-9]
- Delivery Days Customer10
- CAS Number2002381-25-9
- Estimated Purity99.48%
- Molecular FormulaC23H21N3O3
- Molecular Weight387.43
- Scientific DescriptionAPS-2-79 is a KSR-dependent MEK antagonist. APS-2-79 inhibits ATPbiotin binding to KSR2 within the KSR2-MEK1 complexe with an IC50 of 120 nM. APS-2-79 makes the stabilization of the KSR inactive state antagonizes oncogenic Ras-MAPK signaling.
- SMILESCC1=CC(OC2=CC=CC=C2)=CC=C1NC3=NC=NC4=CC(OC)=C(OC)C=C43
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200