APTO-253 [916151-99-0]
HY-16291
CAS Number916151-99-0
Product group Chemicals
Estimated Purity98.15%
Molecular Weight367.38
Overview
- SupplierMedChem Express
- Product NameAPTO-253 [916151-99-0]
- Delivery Days Customer10
- CAS Number916151-99-0
- CertificationResearch Use Only
- Estimated Purity98.15%
- Molecular FormulaC22H14FN5
- Molecular Weight367.38
- Scientific DescriptionAPTO-253 (LOR-253) is a small molecule that inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 mediates anticancer activity through induction of the Krueppel-like factor 4 (KLF4) tumor suppressor. APTO-253 has antiarthritic activity.
- SMILESCC(N1)=C(C(N2)=NC3=C2C4=CC=CN=C4C5=NC=CC=C53)C6=C1C=CC(F)=C6
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200