ARS-853 [1629268-00-3]
HY-19706
Overview
- SupplierMedChem Express
- Product NameARS-853 [1629268-00-3]
- Delivery Days Customer10
- CAS Number1629268-00-3
- Estimated Purity98%
- Molecular FormulaC22H29ClN4O3
- Molecular Weight432.94
- Scientific DescriptionARS-853 is a cell-active, selective, covalent KRAS G12C inhibitor with an IC50 of 2.5 microM. ARS-853 inhibits mutant KRAS-driven signaling by binding to the GDP-bound oncoprotein and preventing activation.
- SMILESClC1=C(C2(C)CC2)C=C(NCC(N3CCN(C4CN(C(C=C)=O)C4)CC3)=O)C(O)=C1
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200