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ARS-853 [1629268-00-3]

HY-19706
MedChem Express
CAS Number1629268-00-3
Product group Chemicals
Estimated Purity98%
Molecular Weight432.94
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    ARS-853 [1629268-00-3]
  • Delivery Days Customer
    10
  • CAS Number
    1629268-00-3
  • Estimated Purity
    98%
  • Molecular Formula
    C22H29ClN4O3
  • Molecular Weight
    432.94
  • Scientific Description
    ARS-853 is a cell-active, selective, covalent KRAS G12C inhibitor with an IC50 of 2.5 microM. ARS-853 inhibits mutant KRAS-driven signaling by binding to the GDP-bound oncoprotein and preventing activation.
  • SMILES
    ClC1=C(C2(C)CC2)C=C(NCC(N3CCN(C4CN(C(C=C)=O)C4)CC3)=O)C(O)=C1
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200