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ProductsBack/Artemisinin [63968-64-9]
Chemical Structure
Chemical Structure
Chemical Structure

Artemisinin [63968-64-9]

Research Use Only
AG-CN2-0467
AdipoGen Life Sciences
CAS Number63968-64-9
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Product group Chemicals
Estimated Purity>98%
Molecular Weight282.3
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Artemisinin [63968-64-9]
  • Delivery Days Customer
    10
  • CAS Number
    63968-64-9
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Hazard Information
    Non-hazardous
  • Molecular Formula
    C15H22O5
  • Molecular Weight
    282.3
  • Scientific Description
    Anti-malaria. Apoptosis inducer. Anti-cancer. Inhibits production of tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), monocyte chemotactic protein-1 (MCP-1) and nitric oxide (NO). Functional ARX inhibitor. Enhancer of GABAA signaling. Shown to promote the in vivo conversion of pancreatic alpha cells into functional beta-like cells through enhanced GABA signaling and may have potential as a therapeutic for diabetes. Targets Gephyrin. - Chemical. CAS: 63968-64-9. Formula: C15H22O5. MW: 282.3. Isolated from Artemisia annua. Anti-malaria. Apoptosis inducer. Anti-cancer. Inhibits production of tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), monocyte chemotactic protein-1 (MCP-1) and nitric oxide (NO).
  • SMILES
    [H][C@@]12CC[C@@H](C)[C@]3([H])CC[C@]4(C)OO[C@@]13[C@]([H])(OC(=O)[C@@H]2C)O4
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200

References

  • Qinghaosu (artemisinin): an antimalarial drug from China: D.L. Klayman; Science 228, 1049 (1985)
  • The development of the antimalarial drugs with new type of chemical structure--qinghaosu and dihydroqinghaosu: Y. Tu; SE Asian J. Trop. Med. Publ. Health 35, 250 (2004)
  • Artemisinin induces apoptosis in human cancer cells: N.P. Singh & H.C. Lai; Anticancer Res. 24, 2277 (2004)
  • Artemisinin attenuates lipopolysaccharide-stimulated proinflammatory responses by inhibiting NF-kappaB pathway in microglia cells: C. Zhu, et al.; PLoS One 7, e35125 (2012)
  • Differential effect of artemisinin against cancer cell lines: M. Tilaoui, et al.; Nat. Prod. Bioprospect. 4, 189 (2014)