ARV-825 [1818885-28-7]

MedChem Express

ARV-825 [1818885-28-7]

10

1818885-28-7

Research Use Only

98.01%

C46H47ClN8O9S

923.43

ARV-825 is a PROTAC connected by ligands for Cereblon and BRD4. ARV-825 binds to BD1 and BD2 of BRD4 with Kds of 90 and 28 nM, respectively.

CC1=NN=C2N1C(SC(C)=C3C)=C3C(C4=CC=C(Cl)C=C4)=N[C@H]2CC(NC5=CC=C(OCCOCCOCCOCCNC6=C(C(N(C7CCC(NC7=O)=O)C8=O)=O)C8=CC=C6)C=C5)=O

2°C to 8°C,-20°C,-80°C

12352200