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Autophinib [1644443-47-9]

HY-101920
MedChem Express
CAS Number1644443-47-9
Product group Chemicals
Estimated Purity99.56%
Molecular Weight346.73
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Autophinib [1644443-47-9]
  • Delivery Days Customer
    10
  • CAS Number
    1644443-47-9
  • Estimated Purity
    99.56%
  • Molecular Formula
    C14H11ClN6O3
  • Molecular Weight
    346.73
  • Scientific Description
    Autophinib is a potent, selective autophagy inhibitor with IC50s of 90 nM and 40 nM for starvation- and Rapamycin-induced autophagy, respectively. Autophinib is also an ATP competitive Vacuolar Protein Sorting 34 (VPS34) inhibitor with an IC50 of 19 nM. Autophinib inhibits autophagy induced by starvation or Rapamycin by targeting VPS34.
  • SMILES
    CC1=CC(NC2=NC(OC3=CC=C([N+]([O-])=O)C=C3)=NC(Cl)=C2)=NN1
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200