Axitinib, Free Base [319460-85-0]
ORB60991
CAS Number319460-85-0
Product group Chemicals
Estimated Purity>99%
Molecular Weight386.47 g/mol
Overview
- SupplierBiorbyt
- Product NameAxitinib, Free Base [319460-85-0]
- Delivery Days Customer16
- CAS Number319460-85-0
- CertificationResearch Use Only
- Estimated Purity>99%
- Molecular FormulaC22H18N4OS
- Molecular Weight386.47 g/mol
- Scientific DescriptionAxitinib (AG-013736) is a multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRbeta and c-Kit with IC50 of 0.1 nM, 0.2 nM, 0.1-0.3 nM, 1.6 nM and 1.7 nM, respectively. Axitinib is currently in Phase III clinical trial in advanced hepatocellular carcinoma. Axitinib is superior as second-line therapy compared with sorafenib, the current standard of care.
- Storage Instruction-20°C or -80°C
- UNSPSC12352200