AZ304 [942507-42-8]
HY-117273
CAS Number942507-42-8
Product group Chemicals
Estimated Purity99.96%
Molecular Weight451.52
Overview
- SupplierMedChem Express
- Product NameAZ304 [942507-42-8]
- Delivery Days Customer10
- CAS Number942507-42-8
- Estimated Purity99.96%
- Molecular FormulaC27H25N5O2
- Molecular Weight451.52
- Scientific DescriptionAZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits wild type BRAF, V600E mutant BRAF and wild type CRAF, with IC50s of 79 nM, 38 nM and 68 nM, respectively. AZ304 also has significant effect on other kinases, such as p38 (IC50, 6 nM), CSF1R (IC50, 35 nM). Anti-tumor activity.
- SMILESO=C(NC1=CC=C(C)C(NC2=C3C=CC(OC)=CC3=NC=N2)=C1)C4=CC=CC(C(C)(C#N)C)=C4
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200