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Vistusertib (AZD2014) [1009298-59-2]

Research Use Only
S2783
Selleck Chemicals
Product group Chemicals
Price on request
Packing Size
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Overview

  • Supplier
    Selleck Chemicals
  • Product Name
    Vistusertib (AZD2014) [1009298-59-2]
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Scientific Description
    Vistusertib (AZD2014) is a novel mTOR inhibitor with IC50 of 2.8 nM in a cell-free assay; highly selective against multiple PI3K isoforms (alfa/bèta/gamma/delta). AZD2014 showed no or weak binding to the majority of kinases when tested at 1 muM. AZD2014 induces proliferation suppression, apoptosis, cell cycle arrest, and autophagy in HCC cells with antitumor activity.
  • UNSPSC
    12352200