Balicatib [354813-19-7]

MedChem Express

Balicatib [354813-19-7]

10

354813-19-7

Research Use Only

98%

C23H33N5O2

411.54

Balicatib (AAE581) is a potent, orally active and selective cathepsin K inhibitor with IC50 values of 22, 61, 48, 2900 nM for cathepsin K, cathepsin B, cathepsin L, cathepsin S, respectively. Balicatib inhibits bone turnover, decreases bone formation rates. Balicatib has the potential for the research of osteoporosis.

CCCN1CCN(C2=CC=C(C(NC3(C(NCC#N)=O)CCCCC3)=O)C=C2)CC1

2°C to 8°C,-20°C,-80°C

12352200