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BAY 11-7082 [19542-67-7]

Research Use Only
HY-13453
MedChem Express
CAS Number19542-67-7
Product group Chemicals
Estimated Purity98.91%
Molecular Weight207.25
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    BAY 11-7082 [19542-67-7]
  • Delivery Days Customer
    10
  • CAS Number
    19542-67-7
  • Certification
    Research Use Only
  • Estimated Purity
    98.91%
  • Molecular Formula
    C10H9NO2S
  • Molecular Weight
    207.25
  • Scientific Description
    BAY 11-7082 is an IkappaBalpha phosphorylation and NF-kappaB inhibitor. BAY 11-7082 selectively and irreversibly inhibits the TNF-alpha-induced phosphorylation of IkappaB-alpha, and decreases NF-kappaB and expression of adhesion molecules. BAY 11-7082 inhibits ubiquitin-specific protease USP7 and USP21 (IC50=0.19, 0.96 microM, respectively). BAY 11-7082 inhibits gasdermin D (GSDMD) pore formation in liposomes and inflammasome-mediated pyroptosis and IL-1beta secretion in human and mouse cells.
  • SMILES
    N#C/C=C/S(=O)(C1=CC=C(C)C=C1)=O
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200