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Copanlisib [1032568-63-0]

HY-15346
MedChem Express
CAS Number1032568-63-0
Product group Chemicals
Estimated Purity98.02%
Molecular Weight480.52
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Copanlisib [1032568-63-0]
  • Delivery Days Customer
    10
  • CAS Number
    1032568-63-0
  • Estimated Purity
    98.02%
  • Molecular Formula
    C23H28N8O4
  • Molecular Weight
    480.52
  • Scientific Description
    Copanlisib (BAY 80-6946) is a potent, selective and ATP-competitive pan-class I PI3K inhibitor, with IC50s of 0.5 nM, 0.7 nM, 3.7 nM and 6.4 nM for PI3Kalpha, PI3Kdelta, PI3Kbeta and PI3Kgamma, respectively. Copanlisib has more than 2,000-fold selectivity against other lipid and protein kinases, except for mTOR. Copanlisib has superior antitumor activity.
  • SMILES
    O=C(C1=CN=C(N)N=C1)NC2=NC3=C(OC)C(OCCCN4CCOCC4)=CC=C3C5=NCCN25
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200