Bazedoxifene [198481-32-2]

MedChem Express

Bazedoxifene [198481-32-2]

10

198481-32-2

Research Use Only

98.7%

C30H34N2O3

470.6

Bazedoxifene (TSE-424) is an oral, BBB-penetrant nonsteroidal selective estrogen receptor modulator (SERM), with IC50s of 23 nM and 99 nM for ERalpha and ERbeta, respectively. Bazedoxifene can be used for the research of osteoporosis. Bazedoxifene also acts as an inhibitor of IL-6/GP130 protein-protein interactions and can be used for the research of pancreatic cancer.

CC1=C(C2=CC=C(O)C=C2)N(CC3=CC=C(OCCN4CCCCCC4)C=C3)C5=CC=C(O)C=C51

2°C to 8°C,-20°C,-80°C

12352200