Bio-Connect

Dactolisib (BEZ235) [915019-65-7]

Research Use Only
S1009
Selleck Chemicals
Product group Chemicals
Price on request
Packing Size
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Overview

  • Supplier
    Selleck Chemicals
  • Product Name
    Dactolisib (BEZ235) [915019-65-7]
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Scientific Description
    Dactolisib (BEZ235, NVP-BEZ235) is a dual ATP-competitive PI3K and mTOR inhibitor for p110alfa/gamma/delta/bèta and mTOR(p70S6K) with IC50 of 4 nM /5 nM /7 nM /75 nM /6 nM in cell-free assays, respectively. Inhibits ATR with IC50 of 21 nM in 3T3TopBP1-ER cell. Dactolisib induces autophagy and suppresses HIV-1 replication. Phase 2.
  • UNSPSC
    12352200