Bio-Connect

BI-3663 [2341740-84-7]

HY-111546
MedChem Express
CAS Number2341740-84-7
Product group Chemicals
Estimated Purity99.9%
Molecular Weight917.84
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    MedChem Express
  • Product Name
    BI-3663 [2341740-84-7]
  • Delivery Days Customer
    10
  • CAS Number
    2341740-84-7
  • Estimated Purity
    99.9%
  • Molecular Formula
    C44H42F3N7O12
  • Molecular Weight
    917.84
  • Scientific Description
    BI-3663 is a highly selective PTK2/FAK PROTAC (DC50=30 nM), with Cereblon ligands to hijack E3 ligases for PTK2 degradation. BI-3663 inhibits PTK2 with an IC50 of 18 nM. BI-3663 is a PROTAC that composes of BI-4464 (HY-124625) linked to Pomalidomide (HY-10984) with a linker. Anti-cancer activity.
  • SMILES
    O=C(NC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)CCOCCOCCOCCNC(C4=CC=C(NC5=NC=C(C(F)(F)F)C(OC6=CC=CC(CC7)=C6C7=O)=N5)C(OC)=C4)=O
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200