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Bimiralisib [1225037-39-7]

Research Use Only
HY-12868
MedChem Express
CAS Number1225037-39-7
Product group Chemicals
Estimated Purity99.8%
Molecular Weight411.38
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Bimiralisib [1225037-39-7]
  • Delivery Days Customer
    10
  • CAS Number
    1225037-39-7
  • Certification
    Research Use Only
  • Estimated Purity
    99.8%
  • Molecular Formula
    C17H20F3N7O2
  • Molecular Weight
    411.38
  • Scientific Description
    Bimiralisib (PQR309) is a potent, brain-penetrant, orally bioavailable, pan-class I PI3K/mTOR inhibitor with IC50s of 33 nM, 451 nM, 661 nM, 708 nM and 89 nM for PI3Kalpha, PI3Kdelta, PI3Kbeta, PI3Kgamma and mTOR, respectively. Bimiralisib is an mTORC1 and mTORC2 inhibitor.
  • SMILES
    NC1=NC=C(C2=NC(N3CCOCC3)=NC(N4CCOCC4)=N2)C(C(F)(F)F)=C1
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200