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ProductsBack/Bisindolylmaleimide II [137592-45-1]
Chemical Structure
Chemical Structure
Chemical Structure

Bisindolylmaleimide II [137592-45-1]

Research Use Only
AG-CR1-0010
AdipoGen Life Sciences
Estimated Purity>97% (mixture of 2 isomers) (NMR)
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Product group Chemicals
Molecular Weight438.5
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Bisindolylmaleimide II [137592-45-1]
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Estimated Purity
    >97% (mixture of 2 isomers) (NMR)
  • Hazard Information
    Non-hazardous
  • Molecular Formula
    C27H26N4O2
  • Molecular Weight
    438.5
  • Scientific Description
    Chemical. CAS: 137592-45-1. Formula: C27H26N4O2. MW: 438.5. Protein kinase C (PKC) inhibitor. Binds with reversed orientation to protein kinase A (PKA). - Protein kinase C (PKC) inhibitor [1, 2]. Binds with reversed orientation to protein kinase A (PKA) [1].
  • SMILES
    CN1CCCC1CCN1C=C(C2=C1C=CC=C2)C1=C(C(=O)NC1=O)C1=CNC2=C1C=CC=C2
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352200

References

  • The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C: D. Toullec, et al.; J. Biol. Chem. 266, 15771 (1991)
  • The protein kinase C inhibitor bisindolyl maleimide 2 binds with reversed orientations to different conformations of protein kinase A: M. Gassel, et al.; J. Biol. Chem. 279, 23679 (2004)