BIX 01294 [1392399-03-9]
S8006
Overview
- SupplierSelleck Chemicals
- Product NameBIX 01294 [1392399-03-9]
- Delivery Days Customer9
- CAS Number1392399-03-9
- CertificationResearch Use Only
- Scientific DescriptionBIX01294 is an inhibitor of G9a histone methyltransferase with IC50 of 2.7 muM in a cell-free assay, reduces H3K9me2 of bulk histones, also weakly inhibits GLP (primarily H3K9me3), no significant activity observed at other histone methyltransferases. BIX01294 induces autophagy. BIX01294 also inhibits H3K36 methylation by oncoproteins NSD1, NSD2 and NSD3.
- UNSPSC12352200