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ProductsBack/BIX 01294 [935693-62-2]
Chemical Structure
Chemical Structure
Chemical Structure

BIX 01294 [935693-62-2]

Research Use Only
AG-CR1-0051
AdipoGen Life Sciences
CAS Number935693-62-2
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Product group Chemicals
Estimated Purity>98% (NMR, HPLC)
Molecular Weight490.6
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    BIX 01294 [935693-62-2]
  • Delivery Days Customer
    10
  • CAS Number
    935693-62-2
  • Certification
    Research Use Only
  • Estimated Purity
    >98% (NMR, HPLC)
  • Hazard Information
    Non-hazardous
  • Molecular Formula
    C28H38N6O2
  • Molecular Weight
    490.6
  • Scientific Description
    Chemical. CAS: 935693-62-2. Formula: C28H38N6O2. MW: 490.6. Selective and cell permeable G9a histone-lysine methyltransferase (HMTase) inhibitor. Does not compete with cofactor S-adenosylmethionine. Pluripotent stem cell inducer. - Selective and cell permeable G9a [Euchromatic Histone-lysine MethylTransferases EHMT2] histone-lysine methyltransferase (HMTase) inhibitor [1]. Does not compete with cofactor S-adenosylmethionine [1]. Pluripotent stem cell inducer [2, 3].
  • SMILES
    [H][C@]12[C@H](C[C@@H](C)C=C1C=C[C@H](C)[C@@H]2CC[C@@H]1C[C@@H](O)CC(=O)O1)OC(=O)[C@@H](C)CC
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352200

References

  • Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase: S. Kubicek, et al.; Mol. Cell 25, 473 (2007)
  • Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds: Y. Shi, et al.; Cell Stem Cell 3, 568 (2008)
  • Activation of pluripotency genes in human fibroblast cells by a novel mRNA based approach: J.R. Plews, et al.; PLoS One 5, e14397 (2010)