BIX-01294 [935693-62-2]
HY-10587
Overview
- SupplierMedChem Express
- Product NameBIX-01294 [935693-62-2]
- Delivery Days Customer10
- CAS Number935693-62-2
- CertificationResearch Use Only
- Estimated Purity98%
- Molecular FormulaC28H38N6O2
- Molecular Weight490.64
- Scientific DescriptionBIX-01294 is a reversible and highly selective G9a and GLP Histone Methyltransferase inhibitor, with IC50s of of 1.7 microM and 0.9 microM, respectively. BIX-01294 inhibits G9a/GLP by competing for binding with the amino acids N-terminal of the substrate lysine residue. BIX-01294, a (1H-1,4-diazepin-1-yl)-quinazolin-4-yl amine derivative, induces necroptosis and autophagy. BIX-01294 has antitumor activity in recurrent tumor cells.
- SMILESCOC1=C(OC)C=C(C(NC2CCN(CC3=CC=CC=C3)CC2)=NC(N4CCN(C)CCC4)=N5)C5=C1
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200