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BIX-01294 [935693-62-2]

Research Use Only
HY-10587
MedChem Express
CAS Number935693-62-2
Product group Chemicals
Estimated Purity98%
Molecular Weight490.64
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    BIX-01294 [935693-62-2]
  • Delivery Days Customer
    10
  • CAS Number
    935693-62-2
  • Certification
    Research Use Only
  • Estimated Purity
    98%
  • Molecular Formula
    C28H38N6O2
  • Molecular Weight
    490.64
  • Scientific Description
    BIX-01294 is a reversible and highly selective G9a and GLP Histone Methyltransferase inhibitor, with IC50s of of 1.7 microM and 0.9 microM, respectively. BIX-01294 inhibits G9a/GLP by competing for binding with the amino acids N-terminal of the substrate lysine residue. BIX-01294, a (1H-1,4-diazepin-1-yl)-quinazolin-4-yl amine derivative, induces necroptosis and autophagy. BIX-01294 has antitumor activity in recurrent tumor cells.
  • SMILES
    COC1=C(OC)C=C(C(NC2CCN(CC3=CC=CC=C3)CC2)=NC(N4CCN(C)CCC4)=N5)C5=C1
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200