Fisogatinib [1707289-21-1]

MedChem Express

Fisogatinib [1707289-21-1]

10

1707289-21-1

98.82%

C24H24Cl2N4O4

503.38

Fisogatinib (BLU-554) is a potent, highly selective and orally active fibroblast growth factor receptor 4 (FGFR4) inhibitor with an IC50 of 5 nM. Fisogatinib has significant anti-tumor activity in models of hepatocellular carcinoma (HCC) that are dependent on FGFR4 signalling.

C=CC(N[C@@H]1[C@H](NC2=NC=C3C=C(C4=C(Cl)C(OC)=CC(OC)=C4Cl)C=CC3=N2)COCC1)=O

2°C to 8°C,-20°C,-80°C

12352200