BML-210 [537034-17-6]

MedChem Express

BML-210 [537034-17-6]

10

537034-17-6

Research Use Only

96.38%

C20H25N3O2

339.43

BML-210 is a potent HDAC inhibitor. BML-210 can inhibit the HDAC4-VP16-driven reporter signal with an apparent IC50 of ~5 microM. BML-210 has a specific disruptive effect on the HDAC4:MEF2 interaction. BML-210 causes an increase in the G0/G1 phase. BML-210 induces apoptosis and displays antitumour activities in orthotopic mammary tumours in mice.

O=C(NC1=CC=CC=C1N)CCCCCCC(NC2=CC=CC=C2)=O

2°C to 8°C,-20°C,-80°C

12352200