BMS-309403 [300657-03-8]
HY-101903
Overview
- SupplierMedChem Express
- Product NameBMS-309403 [300657-03-8]
- Delivery Days Customer10
- CAS Number300657-03-8
- Estimated Purity98%
- Molecular FormulaC31H26N2O3
- Molecular Weight474.55
- Scientific DescriptionBMS-309403 is a potent, orally active and selective adipocyte fatty acid binding protein (also known as FABP4, aP2) inhibitor with Kis of <2, 250, and 350 nM for FABP4, FABP3, and FABP5, respectively. BMS-309403 interacts with the fatty-acid-binding pocket within the interior of the protein and competitively inhibits the binding of endogenous fatty acids. BMS-309403 improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells.
- SMILESO=C(O)COC1=CC(C2=CC=CC=C2N3N=C(C4=CC=CC=C4)C(C5=CC=CC=C5)=C3CC)=CC=C1
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200