BMS-986020 [1257213-50-5]

MedChem Express

BMS-986020 [1257213-50-5]

10

1257213-50-5

98%

C29H26N2O5

482.53

BMS-986020 (AM152) is a high-affinity and selective lysophosphatidic acid receptor 1 (LPA1) antagonist. BMS-986020 inhibits bile acid and phospholipid transporters with IC50s of 4.8 microM, 6.2 microM, and 7.5 microM for BSEP, MRP4, and MDR3, respectively. BMS-986020 has the potential for the treatment of idiopathic pulmonary fibrosis (IPF).

O=C(C1(C2=CC=C(C3=CC=C(C4=C(NC(O[C@@H](C5=CC=CC=C5)C)=O)C(C)=NO4)C=C3)C=C2)CC1)O

2°C to 8°C,-20°C,-80°C

12352200