BMX-IN-1 [1431525-23-3]
HY-80002
CAS Number1431525-23-3
Product group Chemicals
Estimated Purity95.45%
Molecular Weight524.59
Overview
- SupplierMedChem Express
- Product NameBMX-IN-1 [1431525-23-3]
- Delivery Days Customer10
- CAS Number1431525-23-3
- CertificationResearch Use Only
- Estimated Purity95.45%
- Molecular FormulaC29H24N4O4S
- Molecular Weight524.59
- Scientific DescriptionBMX-IN-1 is a selective, irreversible inhibitor of bone marrow tyrosine kinase on chromosome X (BMX) that targets Cys496 in the BMX ATP binding domain with an IC50 of 8 nM, also targets the related Brutons tyrosine kinase (BTK) with an IC50 value of 10.4 nM, but is more than 47-656-fold less potent against Blk, JAK3, EGFR, Itk, or Tec activity.
- SMILESO=C1N(C2=C(C=C1)C=NC3=CC=C(C4=CC=C(NS(=O)(C)=O)C=C4)C=C32)C5=CC=C(C)C(NC(C=C)=O)=C5
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200