Bio-Connect

BMX-IN-1 [1431525-23-3]

Research Use Only
HY-80002
MedChem Express
CAS Number1431525-23-3
Product group Chemicals
Estimated Purity95.45%
Molecular Weight524.59
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    BMX-IN-1 [1431525-23-3]
  • Delivery Days Customer
    10
  • CAS Number
    1431525-23-3
  • Certification
    Research Use Only
  • Estimated Purity
    95.45%
  • Molecular Formula
    C29H24N4O4S
  • Molecular Weight
    524.59
  • Scientific Description
    BMX-IN-1 is a selective, irreversible inhibitor of bone marrow tyrosine kinase on chromosome X (BMX) that targets Cys496 in the BMX ATP binding domain with an IC50 of 8 nM, also targets the related Brutons tyrosine kinase (BTK) with an IC50 value of 10.4 nM, but is more than 47-656-fold less potent against Blk, JAK3, EGFR, Itk, or Tec activity.
  • SMILES
    O=C1N(C2=C(C=C1)C=NC3=CC=C(C4=CC=C(NS(=O)(C)=O)C=C4)C=C32)C5=CC=C(C)C(NC(C=C)=O)=C5
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200