Bortezomib (PS-341) [179324-69-7]
S1013
Overview
- SupplierSelleck Chemicals
- Product NameBortezomib (PS-341) [179324-69-7]
- Delivery Days Customer9
- CAS Number179324-69-7
- CertificationResearch Use Only
- Scientific DescriptionBortezomib (PS-341, Velcade, LDP-341, MLM341, NSC 681239) is a potent 20S proteasome inhibitor with Ki of 0.6 nM. It exhibits favorable selectivity towards tumor cells over normal cells. Bortezomib (PS-341) inhibits NF-kappaB and induces ERK phosphorylation to suppress cathepsin B and inhibit the catalytic process of autophagy in ovarian cancer and other solid tumors.
- UNSPSC12352200