BQ-788 [173326-37-9]

MedChem Express

BQ-788 [173326-37-9]

10

173326-37-9

Research Use Only

98.28%

C34H51N5O7

641.8

BQ-788 is a potent, selective ETB receptor antagonist with IC50 of 1.2 nM for inhibition of ET-1 binding to human Girardi heart cells, poorly inhibiting the binding to ETA receptors in human neuroblastoma cell line SK-N-MC cells with IC50 of 1300 nM.

CCCC[C@H](C(O)=O)NC([C@@H](CC1=CN(C(OC)=O)C2=CC=CC=C12)NC([C@H](CC(C)(C)C)NC(N3[C@H](C)CCC[C@@H]3C)=O)=O)=O

2°C to 8°C,-20°C,-80°C

12352200