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BRD4770 [1374601-40-7]

Research Use Only
HY-16705
MedChem Express
CAS Number1374601-40-7
Product group Chemicals
Estimated Purity98.59%
Molecular Weight413.47
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    BRD4770 [1374601-40-7]
  • Delivery Days Customer
    10
  • CAS Number
    1374601-40-7
  • Certification
    Research Use Only
  • Estimated Purity
    98.59%
  • Molecular Formula
    C25H23N3O3
  • Molecular Weight
    413.47
  • Scientific Description
    BRD4770 is a histone methyltransferase G9a inhibitor. BRD4770 reduces di- and trimethylation of lysine 9 on histone H3 (H3K9) with an EC50 of 5 microM, and has less or little effect toward H3K27me3, H3K36me3, H3K4me3, and H3K79me3. BRD4770 can activate the ataxia telangiectasia mutated (ATM) pathway and induce cell senescence.
  • SMILES
    O=C(C1=CC=C2C(N=C(NC(C3=CC=CC=C3)=O)N2CCCC4=CC=CC=C4)=C1)OC
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200