Brequinar [96187-53-0]

MedChem Express

Brequinar [96187-53-0]

10

96187-53-0

98.59%

C23H15F2NO2

375.37

Brequinar (DUP785) is a potent inhibitor of dihydroorotate dehydrogenase (DHODH) with an IC50 of 5.2 nM for human DHODH. Brequinar has potent activities against a broad spectrum of viruses. Brequinar also has an anti-SARS2 activity.

O=C(C1=C(C)C(C2=CC=C(C3=CC=CC=C3F)C=C2)=NC4=CC=C(F)C=C14)O

2°C to 8°C,-20°C,-80°C

12352200