Chemical Structure
Chemical Structure
Brinzolamide [138890-62-7]
CDX-B0424
CAS Number138890-62-7
Product group Chemicals
Estimated Purity>98%
Molecular Weight383.51
Overview
- SupplierChemodex
- Product NameBrinzolamide [138890-62-7]
- Delivery Days Customer10
- CAS Number138890-62-7
- CertificationResearch Use Only
- Estimated Purity>98%
- Hazard InformationNon-hazardous
- Molecular FormulaC12H21N3O5S3
- Molecular Weight383.51
- Scientific DescriptionBrinzolamide is a potent inhibitor of carbonic anhydrases (IC50=3.2nM and 45.3nM for CAII and CAIV, respectively) that lowers intraocular pressure by locally inhibiting carbonic anhydrase in the ciliary processes and suppressing aqueous humor secretion. Animal studies have found that one week of twice-daily topical ocular treatment with 2% brinzolamide significantly reduced IOP and enhanced optic nerve head blood flow. - Chemical. CAS: 138890-62-7. Formula: C12H21N3O5S3. MW: 383.51. Synthetic. Brinzolamide is a potent inhibitor of carbonic anhydrases (IC50=3.2nM and 45.3nM for CAII and CAIV, respectively) that lowers intraocular pressure by locally inhibiting carbonic anhydrase in the ciliary processes and suppressing aqueous humor secretion. Animal studies have found that one week of twice-daily topical ocular treatment with 2% brinzolamide significantly reduced IOP and enhanced optic nerve head blood flow.
- SMILESO=S(C1=CC2=C(S1)S(N(CCCOC)C[C@@H]2NCC)(=O)=O)(N)=O
- Storage Instruction-20°C
- UNSPSC12352200