BS-181 [1092443-52-1]
HY-13266
CAS Number1092443-52-1
Product group Chemicals
Estimated Purity98.1%
Molecular Weight380.53
Overview
- SupplierMedChem Express
- Product NameBS-181 [1092443-52-1]
- Delivery Days Customer9
- CAS Number1092443-52-1
- CertificationResearch Use Only
- Estimated Purity98.1%
- Molecular FormulaC22H32N6
- Molecular Weight380.53
- Scientific DescriptionBS-181 is a potent and selective CDK7 inhibitor (IC50=21 nM) than Seliciclib (HY-30237). BS-181 is also against CDK2, CDK5 and CDK9 with IC50 values of 880, 3000 and 4200 nM, respectively (fails to block CDK1, 4 and 6). BS-181 inhibits a panel of cancer cells growth (IC50=11.5 microM-37.3 microM) and induces cell apoptosis. BS-181 has the potential for the research of cancer therapy.
- SMILESCC(C1=C(N=C(C=C2NCC3=CC=CC=C3)NCCCCCCN)N2N=C1)C
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200