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BX795 [702675-74-9]

Research Use Only
HY-10514
MedChem Express
CAS Number702675-74-9
Product group Chemicals
Estimated Purity95.86%
Molecular Weight591.47
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    BX795 [702675-74-9]
  • Delivery Days Customer
    10
  • CAS Number
    702675-74-9
  • Certification
    Research Use Only
  • Estimated Purity
    95.86%
  • Molecular Formula
    C23H26IN7O2S
  • Molecular Weight
    591.47
  • Scientific Description
    BX795 is a potent and selective inhibitor of PDK1, with an IC50 of 6 nM. BX795 is also a potent and relatively specific inhibitor of TBK1 and IKKepsilon, with an IC50 of 6 and 41 nM, respectively. BX795 blocks phosphorylation of S6K1, Akt, PKCdelta, and GSK3beta, and has lower selectivity over PKA, PKC, c-Kit, GSK3beta etc. BX795 modulates autophagy.
  • SMILES
    O=C(NCCCNC1=C(C=NC(NC2=CC=CC(NC(N3CCCC3)=O)=C2)=N1)I)C4=CC=CS4
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200