BX795 [702675-74-9]
HY-10514
CAS Number702675-74-9
Product group Chemicals
Estimated Purity95.86%
Molecular Weight591.47
Overview
- SupplierMedChem Express
- Product NameBX795 [702675-74-9]
- Delivery Days Customer10
- CAS Number702675-74-9
- CertificationResearch Use Only
- Estimated Purity95.86%
- Molecular FormulaC23H26IN7O2S
- Molecular Weight591.47
- Scientific DescriptionBX795 is a potent and selective inhibitor of PDK1, with an IC50 of 6 nM. BX795 is also a potent and relatively specific inhibitor of TBK1 and IKKepsilon, with an IC50 of 6 and 41 nM, respectively. BX795 blocks phosphorylation of S6K1, Akt, PKCdelta, and GSK3beta, and has lower selectivity over PKA, PKC, c-Kit, GSK3beta etc. BX795 modulates autophagy.
- SMILESO=C(NCCCNC1=C(C=NC(NC2=CC=CC(NC(N3CCCC3)=O)=C2)=N1)I)C4=CC=CS4
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200