Bio-Connect

C188-9 [432001-19-9]

HY-112288
MedChem Express
CAS Number432001-19-9
Product group Chemicals
Estimated Purity98.11%
Molecular Weight471.52
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    MedChem Express
  • Product Name
    C188-9 [432001-19-9]
  • Delivery Days Customer
    10
  • CAS Number
    432001-19-9
  • Estimated Purity
    98.11%
  • Molecular Formula
    C27H21NO5S
  • Molecular Weight
    471.52
  • Scientific Description
    C188-9 (TTI-101) is a STAT3 inhibitor, with a Kd of 4.7 nM. C188-9 inhibits G-CSF-induced STAT3 activation and STAT3-dependent gene expression. C188-9 induces apoptosis in AML cell lines and primary samples and inhibits colony formation by primary AML blasts.
  • SMILES
    O=S(C1=CC=C(OC)C=C1)(NC2=C3C=CC=CC3=C(O)C(C4=C5C=CC=CC5=CC=C4O)=C2)=O
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200