CCR6 inhibitor 1 [2437547-04-9]
HY-112701
CAS Number2437547-04-9
Product group Chemicals
Estimated Purity99.87%
Molecular Weight504.52
Overview
- SupplierMedChem Express
- Product NameCCR6 inhibitor 1 [2437547-04-9]
- Delivery Days Customer10
- CAS Number2437547-04-9
- Estimated Purity99.87%
- Molecular FormulaC24H23F3N4O3S
- Molecular Weight504.52
- Scientific DescriptionCCR6 inhibitor 1 is a potent and selective CCR6 inhibitor, with IC50s of 0.45 and 6 nM for monkey and human CCR6, much more selective at CCR6 over human CCR1 (IC50, > 30000 nM), and CCR7 (IC50, 9400 nM). CCR6 inhibitor 1 markedly blocks ERK phosphorylation. CCR6 inhibitor 1 is used in the research of autoimmune diseases and cancer.
- SMILESO=S([C@H](CC1)CC[C@@H]1NC2=NC=C(C(F)(F)F)C=C2)(C3=CC=C(C4=CC=NC(C(N)=O)=C4)C=C3)=O
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200