Cediranib (AZD2171) [288383-20-0]
S1017
Overview
- SupplierSelleck Chemicals
- Product NameCediranib (AZD2171) [288383-20-0]
- Delivery Days Customer9
- CAS Number288383-20-0
- CertificationResearch Use Only
- Scientific DescriptionCediranib (AZD2171, NSC-732208) is a highly potent VEGFR(KDR) inhibitor with IC50 of IC50 of 5 nM/≤3 nM, similar activity against c-Kit and PDGFRbèta, 36-, 110-fold and >1000-fold selective more for VEGFR than PDGFR-alfa, CSF-1R and Flt3 in HUVEC cells. Cediranib (AZD2171) induces autophagic vacuole accumulation. Phase 3.
- UNSPSC12352200