CEP-37440 [1391712-60-9]

MedChem Express

CEP-37440 [1391712-60-9]

10

1391712-60-9

Research Use Only

99.58%

C30H38ClN7O3

580.12

CEP-37440 is a potent, orally active dual FAK/ALK inhibitor with IC50 values of 2.3 nM and 3.5 nM for FAK and ALK, respectively. CEP-37440 decreases the cell proliferation by blocking the autophosphorylation kinase activity of FAK1 (Tyr 397).

O=C(NC)C1=CC=CC=C1NC2=NC(NC3=CC=C4C(CCC[C@H](N5CCN(CCO)CC5)C4)=C3OC)=NC=C2Cl

2°C to 8°C,-20°C,-80°C

12352200