Chelerythrine chloride [3895-92-9]

MedChem Express

Chelerythrine chloride [3895-92-9]

10

3895-92-9

Research Use Only

98%

C21H18ClNO4

383.82

Chelerythrine chloride is a potent, cell-permeable inhibitor of protein kinase C, with an IC50 of 660 nM. Chelerythrine chloride inhibits the Bcl-XL-Bak BH3 peptide binding with IC50 of 1.5 microM and displaces Bax from Bcl-XL. Chelerythrine chloride induces apoptosis and autophagy.

C[N+]1=CC2=C(C(OC)=CC=C2C3=C1C4=CC5=C(OCO5)C=C4C=C3)OC.[Cl-]

2°C to 8°C,-20°C,-80°C

12352200