Laduviglusib (CHIR-99021) HCl [1797989-42-4]
S2924
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product NameLaduviglusib (CHIR-99021) HCl [1797989-42-4]
- Delivery Days Customer9
- CertificationResearch Use Only
- Scientific DescriptionCHIR-99021 (CT99021) HCl is hydrochloride of CHIR-99021, which is a GSK-3alfa/bèta inhibitor with IC50 of 10 nM/6.7 nM; CHIR-99021 shows greater than 500-fold selectivity for GSK-3 versus its closest homologs Cdc2 and ERK2. CHIR-99021 is a potent pharmacological activators of the Wnt/beta-catenin signaling pathway. CHIR-99021 significantly rescues light-induced autophagy and augments GR, RORalfa and autophagy-related proteins.
- UNSPSC12352200