Cilomilast [153259-65-5]
HY-10790
CAS Number153259-65-5
Product group Chemicals
Estimated Purity99.89%
Molecular Weight343.42
Overview
- SupplierMedChem Express
- Product NameCilomilast [153259-65-5]
- Delivery Days Customer10
- CAS Number153259-65-5
- CertificationResearch Use Only
- Estimated Purity99.89%
- Molecular FormulaC20H25NO4
- Molecular Weight343.42
- Scientific DescriptionCilomilast (SB-207499) is a potent, selective and orally active inhibitor of Phosphodiesterase 4 (PDE4), with IC50s of ~100 and 120 nM for LPDE4 and HPDE4, respectively. Cilomilast shows selectivity for PDE4 over PDE1, PDE2, PDE3 and PDE5 (IC50=74, 65, >100, and 83 microM, respectively). Cilomilast has anti-inflammatory and immunomodulatory effects and can be used for thr research of asthma and chronic obstructive pulmonary disease (COPD).
- SMILESO=C([C@H]1CC[C@@](C#N)(CC1)C2=CC=C(OC)C(OC3CCCC3)=C2)O
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200