Bio-Connect

Cot inhibitor-2 [915363-56-3]

Research Use Only
HY-32018
MedChem Express
CAS Number915363-56-3
Product group Chemicals
Estimated Purity95.14%
Molecular Weight539.43
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    MedChem Express
  • Product Name
    Cot inhibitor-2 [915363-56-3]
  • Delivery Days Customer
    10
  • CAS Number
    915363-56-3
  • Certification
    Research Use Only
  • Estimated Purity
    95.14%
  • Molecular Formula
    C26H25Cl2FN8
  • Molecular Weight
    539.43
  • Scientific Description
    Cot inhibitor-2 is a potent, selective and orally active cot (Tpl2/MAP3K8) inhibitor with an IC50 of 1.6 nM. Cot inhibitor-2 inhibts TNF-alpha production in LPS-stimulated human whole blood with an IC50 of 0.3 microM.
  • SMILES
    N#CC1=C(C2=CC(NCC3=CN(N=N3)C4CCN(CC4)CC)=CC(Cl)=C2N=C1)NC5=CC=C(F)C(Cl)=C5
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200