CP-10 [2366268-80-4]
HY-125835
CAS Number2366268-80-4
Product group Chemicals
Estimated Purity98.22%
Molecular Weight871.94
Overview
- SupplierMedChem Express
- Product NameCP-10 [2366268-80-4]
- Delivery Days Customer10
- CAS Number2366268-80-4
- Estimated Purity98.22%
- Molecular FormulaC44H49N13O7
- Molecular Weight871.94
- Scientific DescriptionCP-10 is a PROTAC connected by ligands for Cereblon and CDK, with highly selective, specific, and remarkable CDK6 degradation (DC50=2.1 nM). It inhibits proliferation of several haematopoietic cancer cells with impressive potency including multiple myeloma, and can still degrades mutated and overexpressed CDK6.
- SMILESCC(C(C1=O)=C(C)C2=CN=C(NC3=CC=C(N4CCN(CC5=CN(CCOCCNC6=CC=CC(C(N7C8CCC(NC8=O)=O)=O)=C6C7=O)N=N5)CC4)C=N3)N=C2N1C9CCCC9)=O
- Storage Instruction-20°C,-80°C
- UNSPSC12352200