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CX-5461 dihydrochloride

Research Use Only
HY-13323A
MedChem Express
Estimated Purity98.07%
Product group Chemicals
Molecular Weight586.54
Price on request
Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    CX-5461 dihydrochloride
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Estimated Purity
    98.07%
  • Molecular Formula
    C27H29Cl2N7O2S
  • Molecular Weight
    586.54
  • Scientific Description
    CX-5461 dihydrochloride is a potent and orally bioavailable inhibitor of Pol I-mediated rRNA synthesis, with IC50s of 142 nM in HCT-116, 113 nM in A375, and 54 nM in MIA PaCa-2 cells, and shows little or no effect on Pol II (IC50 ≥25 microM).
  • SMILES
    [H]Cl.CC1=NC=C(CNC(C2=C3N(C4=NC(N5CCN(CCC5)C)=CC=C4C2=O)C6=C(S3)C=CC=C6)=O)N=C1.[H]Cl
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200